RANGE EXTENSION OF CAVIA TSCHUDII FITZINGER, 1867 (MAMMALIA: CAVIIDAE) AND FIRST RECORD IN CATAMARCA, NORTHWESTERN ARGENTINA

Range extension of Cavia tschudii Fitzinger, 1867 (Mammalia: Caviidae) and first record in Catamarca, northwestern Argentina

We report the Calze first record of the genus Cavia and the species Cavia tschudii (Rodentia, Caviidae) in Catamarca province, northwestern Argentina, which represents a range extension of about 110 km southward for the species.The cranial and dental remains were recovered from an owl pellet Bars sample found in eastern slopes of the Ambato range,

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Rescue of in vitro models of CSF1R-related adult-onset leukodystrophy by iluzanebart: mechanisms and therapeutic implications of TREM2 agonism

Abstract Microglia dysfunction is implicated in several neurodegenerative disorders, including a rare microgliopathy; CSF1R-related adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (CSF1R-ALSP).CSF1R-ALSP is caused by heterozygous loss-of-function mutations in the colony stimulating factor 1 receptor (CSF1R) gene, which enco

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Personal brand - tool or culmination of professional development?

Objectives Personal branding, which is often considered a personal promotion tool, is such a capacious concept that the promotional aspect alone does not seem to capture the complexity of the practices that lead to a strong personal brand.Undoubtedly, a personal brand influences how an individual shapes his or her career.However, a personal brand i

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Seasonal controls override forest harvesting effects on the composition of dissolved organic matter mobilized from boreal forest soil organic horizons

Dissolved organic matter (DOM) mobilized from the organic (O) horizons of forest soils is a temporally dynamic flux of carbon (C) and nutrients, and the fate of this DOM in downstream pools is dependent on the rate and pathways of water flow as well as its chemical composition.Here, we present observations of the composition of DOM mobilized weekly

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Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation

Abstract Mutations in the Cockayne Syndrome group B (CSB) gene cause cancer in mice, but premature aging and severe neurodevelopmental defects in humans.CSB, a member of the SWI/SNF family of chromatin remodelers, plays diverse roles in regulating gene expression and transcription-coupled nucleotide excision repair (TC-NER); however, these function

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